258. Yuan G, Gruner-Regel I, Lian F, Friedrich T, Hofheinz R, Langer R, Röcken C, Zimmermann W, Schmid RM, Ebert MPA, Burgermeister E. WNT6 is a novel target gene of caveolin-1 promoting chemoresistance to epirubicin in human gastric cancer cells. Oncogene. 2012; Im Druck
257. Harder J,Ihorst G, Heinemann V, Hofheinz R, Moehler M, Buechler P, Kloeppel G, Röcken C, Bitzer M, Boeck S, Endlicher E, Reinacher-Schick A, Schmoor C, Geissler M. Multicentre phase II trial of trastuzumab and capecitabine in patients with HER2 overexpressing metastatic pancreatic cancer. Br J Cancer. 2012; Im Druck
256. Ehling R, Helbok R, Beer R, LacknerP, Broessner G, Pfausler B, Röcken C,Aguzzi A, Chemelli A, Schmutzhard E. Recurrent intracerebral haemorrhage after coitus: a case report of sporadic cerebral amyloid angiopathy in a younger patient. Eur J Neurol. 2012 Mar;19(3):e29-31.
255. Kristen AV, Röcken C. Amyloidose des Herzens. Pathologe. 2012 Feb 10. [Epub ahead of print]
254. Kreipe HH, Röcken C. Qualitätssicherungund Referenzbeurteilung in der Onkologischen Pathologie. Forum 2012;27:33-37
253. Ebert MPA,Tänzer M, Balluff B, Burgermeister E, Kretzschmar AK, Hughes DJ, Tetzner R,Lofton-Day C, Rosenberg R, Reinacher-Schick AC, Schulmann K, Tannapfel A,Hofheinz R, Röcken C, Keller G, Langer R, Specht K, Porschen R,Stöhlmacher-Williams J, Schuster T, Struble RG, Schmid RM TFAP2E-DKK4 and Chemoresistance in Colorectal Cancer. N. Engl. J. Med. 2012; 366:44-53
252. Schönland S, Hegenbart U, Bochtler T, Mangatter A, Hansberg O, Ho AD, Lohse P, Röcken C. Immunohistochemistry in the classification of systemic forms of amyloidosis: a systematic investigation of 117 patients. 2012 Jan 12;119(2):488-93. Epub 2011 Nov 21
251. Ammerpohl O, Pratschke J, Schafmayer C, Haake A, FaberW, von Kampen O, Brosch M, von Schoenfels W, Sipos B, Balschun K, Röcken C,Arlt A, Schniewind B, Grauholm J, Kalthoff H, Neuhaus P, Stickel F, SchreiberS, Becker T, Siebert R, Hampe J. DistinctDNA methylation patterns in cirrhotic liver and hepatocellular carcinoma.IntInt J Cancer. 2012 Mar 15;130(6):1319-28. doi: 10.1002/ijc.26136. Epub 2011 Jul 21.
2011
250. Warneke VS, Behrens HM, Hartmann J, Held H, Becker T, Schwarz NT, Röcken C. Reply to A. Biondi et al and J. Deng et al. J Clin Oncol. 2011;29(32):4340-4342
249. Balschun K, Wenke AK, Röcken C, Haag J. Detection of KRAS and BRAF mutations in advanced colorectal cancer by allele-specific single-base primer extension. Expert Rev Mol Diagn. 2011 Nov;11(8):799-802.
248. Kristen AV, Katus HA, Röcken C, Altland K. Therapie der Thransthyretin-Amyloidose: Grüner Tee als Oprion? DNP - Der Neurologe & Psychiater 2011;12:7-8
247. Balschun K, Röcken C. Filiforme Polypose. Eine seltene Komplikation bei Patienten mit chronisch entzündlicher Darmerkrankung. Gastroenterologie up2date. 2011;7:166-170.
246. Kristen AV, Haufe S, Schönland SO, Hegenbart U, Schnabel PA, Röcken C, Hardt S, Lohse P, Ho AD, Haberkorn U, Dengler TJ, Altland K, Katus HA. Skeletal scintigraphy indicates disease severity of cardiac involvement in patients with senile systemic amyloidosis. Int J Cardiol. 2011 Jul 15. [Epub ahead of print]
245.Röcken C. Die Rolle der Mikro-RNA bei der Entstehung onkologischer Erkrankungen. Der Onkologe. 2011;17(6):487-494
244. Balschun K, Haag J, Wenke AK, von Schönfels W, Schwarz NT, Röcken C. KRAS-, NRAS-, PIK3CAexon 20- and BRAF-genotype in synchronousand metachronous primary colorectal cancers – diagnostic and therapeuticimplications. J Mol Diagn. 2011;13(4):436-45
243.Burgermeister E, Friedrich T, Hitkova I, Gruner I, EinwächterH, Zimmermann W, Röcken C, Perren A,Wright MB, Schmid RM, Seger R, Ebert MPA. The ras inhibitors caveolin-1 and docking protein-1 activate PPARgammathrough spatial relocalization at helix-7 of its ligand-binding domain. Mol Cell Biol. 2011;31(16):3497-510
242. Lian F, Xing X, Yuan G, Schäfer C, Rauser S, Walch A, Röcken C, Ebeling M, Wright MB, Schmid RM, Ebert MPA, Burgermeister E. Farnesoid X receptor protects human and murine gastric epithelial cells against inflammation-induced damage. Biochem J. 2011;438(2):315-23.
241. Warneke V, Behrens HM, Hartmann JT, Held H, Becker T,Schwarz NT, Röcken C. A cohort study based on the 7th edition of the TNMclassification for gastric cancer: proposal of a new staging system. J Clin Oncol. 2011;29(17):2364-71
240. Cordes C, Häsler R, Werner C,Görögh T, Röcken C, Hebebrand L,Kast WM, Hoffmann M, Schreiber S, Ambrosch. The level of secretory leukocyte protease inhibitor is decreased in metastatic headand neck squamous cell carcinoma. Int J Oncol. 2011;39(1):185-91
239. Möhler M etal. S3-Leitlinie Magenkarzinom. Diagnostik und Therapieder Adenokarzinome des Magens und ösophagogastralen Übergangs. Z Gastroenterol. 2011;49(4):461-531
238. Stecker K, Vieth M, Koschel A, Wiedenmann B, Röcken C, Anders M.Impact of the coxsackievirus and adenovirus receptor on the adenoma-carcinoma sequence of colon cancer. Br J Cancer. 2011;104(9):1426-33
237. Schmuck R, Warneke V, Behrens
HM, Weichert W, Röcken C. Genotypic and
phenotypic characterization of the side population of gastric cancer.
Am J Pathol. 2011;178(4):1792-1804
236. Kieninger B, Gioeva Z, Krüger S, Westermark G, Friedrich RP, Fändrich M, Röcken C.PTAA and B10: new approaches to amyloid detecteion in tissue. Evaluation of amyloid detection in tissue with a conjugated polyelectrolyte and a fibril-specific antibody fragment. Amyloid. 2011;18(2):47-52
235. Haupt C, Bereza M, Kumar ST, Kieninger B, Morgado I, HortschanskyP, Fritz G, Röcken C, Horn C, FändrichM. Pattern recognition with a fibril-specific antibody fragment reveals the surfacevariability of natural amyloid fibrils. J Mol Biol. 2011;408(3):529-40
234. Jann H, Roll S, Couvelard A, Hentic O, Pavel M, Müller-Nordhorn J, Koch M, Röcken C, Rindi G, Ruszniewski P, Wiedenmann B, Pape UF. Neuroendocrine tumors of mid- and hindgut origin:TNM-classification determines clinical outcome. Cancer. 2011;117(15):3332-41
233. Kohler I, Jacob D, Budzies J, Lehmann A, Weichert W, Schulz S, Neuhaus P, Röcken C. Phenotypic and genotypic characterization of carcinomas of the papilla of Vater has prognostic and putative therapeutic implications. Am J Clin Pathol. 2011;135(2):202-11
232. Herpel E, Röcken C, Manke H, Schirmacher P, Flechtenmacher C. Letter to the editor-reply to comments of Carter et al. Virchows Arch 2011;458(2):249-50
231. Kasajima A, Pavel M, Darb-Esfahani S,Noske A, Stenzinger A, Sasano H, Dietel M, Denkert C, Röcken C, Wiedenmann B, Weichert W. mTOR expression and activity patterns in gastroenteropancreatic neuroendocrine tumors. Endocr Relat Cancer. 2011;18(1):181-92.
230. Gabbert HE, Röcken C. Her2. Ein neuer prädiktiver Biomarker in der Behandlung des metastasierten Magenkarzinoms. Forum. 2011;25:48-49
2010
229. Röcken C, Rüschoff J. Identifikationtherapeutischer Zielstrukturen: EGFR, Her2 und EpCamIn: Lordick F(Hrsg.). Biologie und zielgerichtete Therapie des Magenkarzinoms. UNI-MED,Bremen, 2010; S. 38-45
228. Endo J, Röcken C, Lamb S, Harris RM, Bowen AR. Nodular amyloidosis in a diabetic patient with frequent hypoglycemia: sequela of repeatedly injecting insulin without site rotation. J Am Acad Dermatol. 2010;63(6):e113-4
227. Balluff B, Elsner M, Kowarsch A,Rauser S, Meding S, Schuhmacher C, Feith M, Herrmann K, Röcken C, Schmid RM, Höfler H, Walch A, Ebert MPA. Classification of HER2/neu status in gastric cancerusing a breats-cancer derived proteome classifier. J Proetome Res. 2010;9(12):6317-6322
226. Herpel E, Röcken C, Manke H, Schirmacher P,Flechtenmacher. Quality Management and Accreditation of Research Tissue Banks. Virchows Arch. 2010;457(6):741-7
225. Tchernitsa O, Kasajima A,Schäfer R, Kuban RJ, Ungethüm U, Györffy B, Neumann U, Simon E, Weichert W,Ebert MPA, Röcken C. Systematicevaluation of the miRNA-ome and downstream effects on mRNA expressionidentifies gastric cancer progression. J Pathol. 2010;222(3):310-9.
224. Lordick F, Grenacher L, Röcken C, Ebert M, Moehler M, Schumacher G. Diagnostik und Therapie des Magenkarzinoms. Dtsch Med Wochenschr. 2010;135(34/35):1671-1682
223.Röcken C. Amyloid und Amyloidosen des Gastrointestinaltrakts. Verdauungskrankheiten. 2010;4:154-158
222. Berndt U, Philipsen L, Bartsch S, Hu Y, Röcken C, Wiedenmann B, Haemmerle M, Rösch T, Sturm A. Comparative Multi-Epitope-Ligand-Cartography reveals essential immunological alterations in Barrett's metaplasia and esophageal adenocarcinoma. Mol Cancer. 2010;9(1):177
221. Kristen AV, Giannitsis E, Schönland S, Hegenbart U, LehrkeS, Konstandin M, Lindenmaier D, Merkle C, Hardt C, Röcken C, Schnabel P, Ho A, Dengler T, Katus. Assessment of Disease Severity and Outcome in Patients with SystemicLight-Chain Amyloidosis by the High-sensitivity Troponin-T Assay. Blood. 2010;116(14):2455-61
220. Csepregi A, Ebert MP, Röcken C, Schneider-Stock R,Hoffmann J, Schulz HU, Roessner A, Malfertheiner P. Promotermethylation of CDKN2A and lack of p16 expression characterize patients withhepatocellular carcinoma. BMC Cancer. 2010;10(1):317
219. Schmeding M, Kienlein S, Röcken C, Neuhaus R, Neuhaus P, Heidenhain C, Neumann UP. ELISA-based detection of C4d after liver transplantation - a heplful tool for differential diagnosis between acute rejection and HCV-recurrence? Transpl Immunol.2010;23(4):156-60
218. Ingold B, Simon E, Ungethüm U, Kuban RJ, Müller BM, Lupp A, Neumann U, Ebert MPA, Denkert C, Weichert W, Schulz S, Röcken C. Vascular CXCR4 expression – a novel antiangiogenic target in gastric cancer? PLoS One. 2010;5(4):e10087
217. Kieninger B, Eriksson M, Kandolf R, Schnabel P, Schönland S, Hegenbart U, Lohse P, Röcken C. Amyloid in endomyocardial biopsies.Virchows Archiv. 2010;456(5):523-32
216. Lupp A, Klenk C, Röcken C, Evert M, Mawrin C, Schulz S. Immunohistochemical identification of the PTHR1 parathyroid hormone receptor in normal and neoplastic human tissues. Eur J Endocrinol. 2010;162(5):979-86
215. Tänzer M, Balluff B, Distler J, Hale K, Leodolter A, Röcken C, Molnar B, Schmid R, Lofton-Day C, Schuster T, Ebert MPA. Performance of Epigenetic Markers SEPT9 and ALX4 in Plasma for Detection of Colorectal Precancerous Lesions. PLoS One 2010; 5(2): e9061.
214. Schmeding M, Rademacher S, Boas-Knoop S, Röcken C, Lendeckel U, Neuhaus P, Neumann UP. rHuEPo reduces ischemia-reperfusion injury and improves survival after transplantation of fatty livers in rats. Transplantation. 2010;89(2):161-8.
213. Nilsson KPR, Ikenberg K, Aslund A, Fransson S, Konradsson P, Röcken C, Moch H, Aguzzi A. Structural typing of systemic amyloidoses by luminescent conjugated polymer spectroscopy. Am J Pathol. 2010;176(2):563-74.
212.Röcken C, Manke H. Akkreditierung in der Pathologie. Der Pathologe. 2010;31(4):268-78
211. Weichert W, Schewe C, Lehmann A, Sers C, Denkert C, Budczies J, Stenzinger A, Joos H, Landt O, Heiser V, Röcken C, Dietel M. KRAS genotyping of paraffin embedded colorectal cancer tissue in routine diagnostics. Comparison of methods and impact of histology. J Mol Diagn. 2010;12(1):35-42
210. Kozian A, Schilling T, Röcken C, Breitling C, Hachenberg T, Hedenstierna G. Increased alveolar damage after mechanical ventilation ion a porcine model of thoracic surgery. J Cardiothorac Vasc Anesth. 2010;24(4):617-623
209. Gräntzdörffer I, Yumlu S, Gioeva Z, von Wasielewski R, Ebert MP, Röcken C. Comparison of different tissue sampling methods for protein extraction from formalin-fixed and paraffin-embedded tissue specimens. Exp Mol Pathol. 2010; 88:190-196
2009
208. Kamphues C, Bova R, Röcken C, Neuhaus P, Pratschke J, Neumann UP. Safety of mycophenolate mofetil monotherapy in patients after liver transplantation. Ann. Transplantat.2009;14(4):40-6.
207. Franke K, Carl-McGrath S, Röhl FW, Lendeckel U, Ebert M, Tänzer M, Pross M, Röcken C. Differential expression of SPARC in intestinal type gastric cancer correlates with tumor progression and nodal spread. Transl Oncol. 2009;2(4):310-20.
206. Kamphues C, Lotz K, Röcken C, Berg T, Eurich D, Pratschke J, Neuhaus P, Neumann UP. Chances and limitations of non-invasive tests in the assessment of liver fibrosis in liver transplant patients. Clin Transplant. 2010;24(5):652-9
205. Ingold B, Schulz S, Budzies J, Neumann U, Ebert M, Weichert W, Röcken C. The role of vascular CXCR4 expression in colorectal carcinoma. Histopathology. 2009;55(5):576-586.
204. Kristen AV, Sack FU, Schönland SO, Hegenbart U, Helmke BM, Koch A, Schnabel PA, Röcken C, Hardt S, Remppis A, Goldschmidt H, Karck M, Ho AD, Katus HA, Dengler TJ. Staged heart transplantation and chemotherapy as treatment option in patients with severe cardiac light-chain amyloidosis. Eur J Heart Fail. 2009;11(10):1014-20.
203. Röcken C. Update – Immuhistologische Klassifikation der Amyloidosen. Der Pathologe. 2009;30 Suppl 2:121-3
202. Yumlu S, Barany R, Eriksson M, Röcken C. Localized insulin-derived amyloidosis in patients with diabetes mellitus: A report of four cases. Human Pathol. 2009;40(11):1655-60. Epub 2009 Aug 14.
201. Ng E, Tsang W, Ng SS, Jin H, Yu J, Li JJ, Röcken C, Ebert MPA, Kwok TT, Sung JJY. MicroRNA-143 targets DNA methytransferase 3A in colorectal cancer. Br J Cancer. 2009;101(4):699-706
200. von Hutten H, Mihatsch M, Lobeck H, Rudolph B, Eriksson M, Röcken C. Prevalence and origin of amyloid in kidney biopsies. Am J Surg Pathol. 2009;33(8):1198-205
199. Neumann U, Thelen A, Röcken C, Bahra M, Riess H, Jonas S, Schmeding M, Pratschke J, Bova R, Neuhaus P. Non-response to preoperative chemotherapy does not preclude long-term survival after liver resection in patients with colorectal liver metastases. Surgery. 2009 Jul;146(1):52-9. Epub 2009 Apr 21.
198. Babilas P, Fiebig B, Aslanidis C, Hansen J, Röcken C, Schröder J, Schmitz G, Weber B, Landtaler M, Vogt T. Identification of an oncostatin M receptor mutation associated with familial primary cutaneous amyloidosis. Br J Dermatol. 2009 Oct;161(4):944-7. Epub 2009 May 21. No abstract available
197. Carl-McGrath S, Gräntzdörffer I, Ebert MPA, Röcken C. Angiotesnin II-generating enzymes, angiotensin-converting enzyme (ACE) and mast-cell chymase (CMA1) in gastric inflammation may be regulated by pylori H. and associated cytokines. Pathology. 2009 May 6:1-9
196. Gioeva Z, Kieninger B, Röcken C. Amyloidosis in liver biopsies. Der Pathologe. 2009 May;30(3):240-5
195. Le Coutre P, Meisel H, Hofmann J, Röcken C, Vuong LG, Neuburger S, Hemmati PG, Dörken B, Arnold R. Reactivation of hepatitis E infection in a patient with acute lymphoblastic leukemia after allogeneic stem cell transplantation. Gut. 2009 May;58(5):699-702
194. Carl M, Röcken C, Spuler S. Amyloidose bei Muskeldystrophie. Der Pathologe. 2009 May;30(3):235-9
193. Eriksson M, Schönland S, Yumlu S, Hegenbart U, Gioeva Z, Lohse P, Büttner J, Schmidt H, Röcken C. Hereditary apolipoprotein AI-associated amyloidosis in surgical pathology specimens: Identification of three novel mutations in the APOAI-gene. J Mol Diagn. 2009 May; 11(3):257-62
192. Röcken C, Eriksson M. Amyloid und Amyloidosen. Der Pathologe. 2009 May;30(3):182-92
191. Röcken C. Amyloid und Amyloidosen in der Pathologe. Der Pathologe. 2009 May;30(3):173-4
190. Röcken C, Widulin N, Schnalke T. Die Amyloidosen des Berliner Medizinhistorischen Museums der Charité. Der Pathologe. 2009 May;30(3):226-34.
189. Bukowska A, Röcken C, Erxleben M, Röhl FW, Huth C, Ebert MPA, Lendeckel U, Goette A. Atrial expression of endothelial nitric oxide synthase in patients with and without atrial fibrillation. Cardiovasc Pathol. 2009 Feb 10. [Epub ahead of print]
188. Xing X, Burgermeister E, Geisler F, Einwächter F, Fan L, Hiber M, Rauser S, Walch A, Röcken C, Ebeling M, Wright MB, Schmid RM, Ebert MPA. Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver hypertrophy. Hepatology. 2009 Mar;49(3):979-88
187. Anders M, Vieth M, Röcken C, Ebert M, Pross M, Gretschel S, Schlag PM, Wiedenmann B, Kemmner W, Höcker M. Loss of coxsackie and adenovirus receptor contributes to gastric cancer progression. Br J Cancer. 2009 Jan 27;100(2):352-9. Epub 2009 Jan 13.
186. Yu J, Tao Q, Cheng YY, Lee KY, Ng SS, Cheung KF, Tian L, Rha SY, Neumann U, Röcken C, Ebert MPA, Chan FKL, Sung JJY. Promoter methylation of a Wnt/b-catenin signaling antagonist DKK3 is associated with poor survival of gastric cancer. Cancer. 2009 Jan 1;115(1):49-60.
185. Kühlmann UC, Chwieralski CE, van den Brule S, Röcken C, Reinhold D, Welte T, Bühling F. Modulation of cytokine production and silica-induced lung fibrosis by inhibitors of aminopeptidase N and of dipeptidyl peptidase-IV-related proteases. Life Sci. 2009 Jan 2;84(1-2):1-11. Epub 2008 Oct 17
184. Eriksson M, Büttner J, Todorov T, Yumlu S, Schönland S, Hegenbart U, Kristen AV, Dengler T, Lohse P, Haas J, Helmke B, Schmidt H, Röcken C. Prevalence of germline mutations in the TTR gene in a consecutive series of surgical pathology specimens with ATTR amyloid. Am J Surg Pathol. 2009 Jan;33(1):58-65.
183. Erbersdobler A, Kollermann J, Graefen M, Röcken C, Schlomm T. Seminal Vesicle amyloidosis does not protect from invasion by prostate cancer.BJU Int. 2009 Feb;103(3):324-6. Epub 2008 Sep 3
182. Mantke R, Schubert D, Röcken C, Paege I, Halangk W, Peters B, Lippert H, Schulz HU. Caerulein or taurocholate induced enzymatic and histologic alterations in the isolated perfused rat pancreas. 2009 Mar;394(2):363-9. Epub 2008 Aug 9
181. Kamphues CH, Röcken C, Neuhaus P, Neumann UP. Non-functioning, malignant pancreatic neuroendocrine tumour (PNET): a rare entity during pregnancy. Langenbecks Arch Surg. 2009 Mar;394(2):387-91. Epub 2008 May 30
2008
180. McGough JM, Yang D, Huang S, Georgi D, Hewitt SM, Röcken C, Tänzer M, Ebert MPA, Liu K. DNA Methylation Represses IFN-{gamma}-Induced and Signal Transducer and Activator of Transcription 1-Mediated IFN Regulatory Factor 8 Activation in Colon Carcinoma Cells. Mol Cancer Res. 2008 Dec;6(12):1841-51.
179. Deininger SO, Ebert MPA, Fütterer A, Gerhard M, Röcken C. MALDI imaging combined with hierarchical clustering as a new tool for the interpretation of complex human cancers. J Proteome Res. 2008; 7 (12): 5230–5236
178. Kolfenbach S, Mönkemüller K, Röcken C, Malfertheiner P. Whipple's Disease: Magnification Endoscopy and Histological Characteristics. Endoscopy. 2008 Sep;40 Suppl 2:E112. Epub 2008 May 8.
177. Röcken C. Molekulare Targets beim Kolonkarzinom: VEGF, EGFR - was noch? Der Pathologe. 2008 Nov;29 Suppl 2:200-3.
176. Ivanauskas A, Hoffmann J, Jonaitis LV, Markelis R, Juozaityte E, Kupcinskas L, Lofton-Day C, Röcken C, Malfertheiner P. Distinct TPEF/HPP1 gene methylation patterns in gastric cancer indicate a field effect in gastric carcinogenesis. Dig Liver Dis. 2008 Dec;40(12):920-6. Epub 2008 Sep 16
175. Röcken C. Pathologie der Amyloidosen. Der Nephrologe. 2008; 3(4): 275-284
174. Yu J, Tao Q, Cheung KF, Jin H, Poon FF, Wang X, Li H, Cheng YY, Röcken C, Ebert MPA, Chan AT, Sung JJY. Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors. Hepatology. 2008 Aug;48(2):508-18.
173. Manke H, Röcken C. Akkreditierung in der Pathologie. Der Pathologe. 2008; Sep;29(5):388-402.
172. Gu P, Xing X, Tänzer M, Röcken C, Weichert W, Ivanauskas A, Pross M, Peitz U, Malfertheiner P, Schmid R, Ebert MPA. Frequent loss of TIMP-3 expression in progression of esophageal and gastric adenocarcinomas. Neoplasia. 2008; 10(6): 563-572
171. Wex T, Ebert MPA, Kropf S, Dierkes J, Schüttler K, Röcken C, Höcker M, Malfertheiner P. Gene polymorphisms of the NOD-2/CARD-15 gene and the risk of gastric cancer in Germany. Anticancer Res. 2008;28:757-762
170. Pape UF, Jann H, Müller-Nordhorn J, Bockelbrink A, Berndt U, Willich SN, Koch M, Röcken C, Rindi G, Wiedenmann B. Prognostic relevance of a proposed TNM-classification system for gastroenteropancreatic neuroendocrine tumors of foregut origin. Cancer 2008 July 15; 113(2): 256-65
169. Eriksson M, Schönland S, Bergner R, Hegenbart U, Lohse P, Schmidt H, Röcken C. Renal fibrinogen Aα-chain amyloidosis – the first three German cases with the p.Glu526Val mutation. Virchows Arch. 2008 July; 453(1):25-31
168. Burgermeister E, Liscovitch M, Röcken C, Schmid RM, Ebert MPA. Caveats of caveolin-1 in cancer progression. Cancer Letters. 2008 Sep 18;268(2):187-201.
167. Qiao L, Dai Y, Gu Q; Chan KW, Ma J; Lan HY, Zou B, Röcken C, Ebert MPA, Wong BC. Loss of XIAP sensitizes colon cancer cells to PPARg independent anti-tumor effects of troglitazone and 15-PGJ2. Cancer Letters. 2008 Sep 18;268(2):260-71
166. Gräntzdörffer I, Carl-McGrath S, Ebert MPA, Röcken C. Proteomics of pancreatic cancer - a review. Pancreas. 2008; 36(4):329-336
165. Röcken C, Ketterlinus R, Ebert M. Application of proteome analysis to the assessment of prognosis and response prediticion in clinical oncology. Curr Cancer Drug Targets. 2008 Mar;8(2):141-5
164. Kozian A, Schilling T, Hedenstierna G, Röcken C, Fredén F, Maripuu E, Hachenberg T. One-Lung Ventilation Induces Persistent Hyperperfusion and Alveolar Damage in the Ventilated Lung - an Experimental Study. Br J Anaesthesia. 2008 Apr;100(4):549-59
163. Spuler S, Carl M, Zabojszcza J, Straub V, Bushby K, Moore S, Bähring S, Wenzel K, Vinkemeier U, Röcken C. Dysferlin-deficient muscular dystrophy features amyloidosis. Ann Neurology. 2008 Mar;63(3):323-8
162. Röcken C, Neumann U, Ebert M. Neue Wege zur Früherkennung, Prognoseabschätzung und Therapie maligner Tumoren des Gastrointestinaltrakts. Z. Gastroenterol. 2008 Feb;46(2):216-22
161. Goette A, Bukowska A, Lendeckel U, Erxleben M, Hammwöhner M, Strugala D, Pfeiffenberger J, Röhl FW, Huth C, Ebert MPA, Klein HU, Röcken C. Angiotensin II receptor blockade reduces tachycardia–induced atrial adhesion molecule expression. Circulation. 2008 Feb 12;117(6):732-42.
160. Weichert W, Röske A, Gekeler V, Beckers T, Ebert MPA, Pross M, Dietel M, Denkert C, Röcken C. Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: a retrospective analysis. Lancet Oncol. 2008 Feb;9(2):139-48.
159. Röcken C, Ebert MPA. Postoperative staging of pancreatic cancer. Recent Results in Cancer Research. 2008;177:39-48.
158. Carl-McGrath S, Schneider-Stock R, Ebert M, Röcken C. Differential expression and localization of gasdermin-like (GSDML), a novel member of the cancer-associated GSDMDC protein family, in neoplastic and non-neoplastic gastric, hepatic and colon tissues. Pathology. 2008;40(1):13-24.
157. Csepregi A, Röcken C, Hoffmann J, Gu P, Saliger S, Müller O, Schneider-Stock R, Kutzner N, Roessner A, Malfertheiner P, Ebert MPA. APC promoter methylation and protein expression in hepatocellular carcinoma. J Cancer Res Clin Oncol. 2008 May;134(5):579-89.
2007
156. Carl-McGrath, Ebert M, Röcken C. Gastric adenocarcinoma: epidemiology, pathology and pathogenesis. Cancer Therapy. 2007;5:879-896
155. Habicht G, Haupt C, Friedrich RP, Hortschansky P, Sachse C, Meinhardt J, Wieligmann K, Gellermann GP, Brodhun M, Götz J, Grigorieff N, Halbhuber KJ, Röcken C, Horn U, Fändrich M. Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Ab protofibrils. Proc. Natl. Acad. Sci. U.S.A. 2007;104(49):19232-7.
154. Carl-McGrath S, Ebert MPA, Lendeckel U, Röcken C. Expression of the local angiotensin II system in gastric cancer may facilitate lymphatic invasion and nodal spread. Cancer Biol Ther. 2007; 6(8) [Epub ahead of print]
153. Ebert MP, Schmid R, Röcken C. Need for a paradigm shift in cancer prevention and clinical oncology. Expert Rev Anticancer Ther. 2007 Oct;7(10):1363-7
152. Röcken C, Neumann K, Carl-McGrath S, Lage H, Ebert MPA, Dierkes J, Jacobi CA, Kalmuk S, Neuhaus P, Neumann U. The Gene Polymorphism of the Angiotensin I-Converting Enzyme correlates with Tumor Size and Patient Survival In Colorectal Cancer Patients. Neoplasia. 2007; 9(9):716-22
151. Röcken C, Neumann U. Anatomie der Leber und Pathologie der Lebertumoren. Viszeralchirurgie. 2007; 42:215-222
150. Burgermeister E, Xing X, Röcken C, Juhasz M, Chen J, Hiber M, Mair K, Shatz M, Liscovitch M, Schmid RM, Ebert MP. Differential expression and function of caveolin-1 in human gastric cancer progression. Cancer Res. 2007; 67(18): 8519-26
149. Treiber G, Röcken C, Wex T, Malfertheiner P. Octreotide Alone or in Combination with Rofecoxib as Palliative Treatmentfor Advanced Hepatocellular Cancer. Z Gastroenterol. 2007;45(5):369-77
148. Bellutti M, Weigt J, Mönkemüller K, Röcken C, Wieners G, Dombrowski F, Malfertheiner P. Localized primary AL-type amyloidosis of the jejunum diagnosed by double-balloon enteroscopy. Endoscopy. 2007 Feb;39 Suppl 1:E134-5. Epub 2007 Jul 9.
147. Röcken C, Röhl FW, Diebler E, Lendeckel U, Pross M, Carl-McGrath S, Ebert MPA. The angiotensin II/angiotensin II receptor system correlates with nodal spread in intestinal type gastric cancer. Cancer Epidemiol Biomarkers Prev. 2007; 16(6):1206-12
146. Ebert M, Xing X, Burgermeister E, Schmid R, Röcken C. Perspectives of clinical proteomics in gastrointestinal cancer. Exp Rev Anticancer Ther. 2007 Apr;7(4):465-469.
145. Ebert MP, Röcken C. First Steps Towards Molecular Prevention in Gastric Carcinogenesis. Cancer Biol Ther. 2007 Feb;6(2):276-7.
144. Götte A, Lendeckel U, Kuchenbecker A, Bukowska A, Peters B, Klein HU, Huth C, Röcken C. Cigarette smoking induces via nicotine atrial fibrosis. Heart. 2007;93(9):1056-63.
143. Preller V, Gerber A, Wrenger S, Togni M, Marguet D, Tadje J, Lendeckel U, Röcken C, Faust J, Neubert K, Schraven B, Martin R, Ansorge S, Brocke S, Reinhold D. TGF-beta.1-mediated control of CNS inflammation and autoimmunity through the inhibitory receptor CD26. J Immunol. 2007;178(7):4632-40
142. Kuci H, Ebert MPA, Röcken C. Peptide antibodies for the immunohistochemical classification of AL amyloid.Histol Histopathol. 2007; 22(4):379-87
141. Mönkemüller K, Fry LC, Ebert M, Bellutti M, Venerito M, Knippig C, Rickes S, Muschke P, Röcken C, Malfertheiner P. Feasibility of double-balloon enteroscopy-assisted chromoendoscopy of the small bowel in patients with familial adenomatous polyposis. Endoscopy. 2007; 39:52-57
140. Schulz HU, Kellner U, Kahl S, Effenberger O, Asperger W, Lippert H, Röcken C. A giant pancreatic serous microcystic adenoma with 20 years follow-up. Langenbeck's Archives of Surgery. 2007;392(2):209-13
139. Götze T, Röcken C, Röhl FW, Wex T, Hoffmann J, Westphal S, Malfertheiner P, Ebert MPA, Dierkes J. Gene polymorphisms of folate metabolizing enzymes and the risk of gastric cancer. Cancer Letters. 2007 Jun 28;251(2):228-36
138. Obermeyer K, Krüger S, Peters B, Falkenberg B, Roessner A, Röcken C. The Expression of Low Density Lipoprotein Receptor-related Proteins (LRP) in colorectal cancer. Oncol Reports. 2007;17(2):361-7
2006
137. Röcken C, Ernst J. Amyloiddiagnostik bei rheumatischen Erkrankungen. Pathologe. 2006 Nov;27(6):422-30
136. Ebert M, Meyer L, Röcken C. Magen. In: Kahl et al. (Hrsg.) Interventionelle Endoskopie. Lehrbuch und Atlas. Elsevier GmbH, München, 2006
135. Röcken C, Ernst J, Hund E, Michels H, Perz J, Saeger W, Sezer O, Spuler S, Willig F, Schmidt HHJ. Interdisziplinäre Leitlinien zur Diagnostik und Therapie der extrazerebralen Amyloidosen. Med Klin. 2006 Oct 15;101(10):825-9.
134. Röcken C, Fändrich M, Stix B, Tannert A, Hortschansky P, Reinheckel T, Saftig P, Kähne T, Menard R, Ancsin JB, Bühling F. Cathepsin protease activity modulates amyloid-load in extracerebral amyloidosis. J Pathol. 2006 Dec;210(4):478-87
133. Ebert MPA, Model F, Mooney S, Hale K, Lograsso K, Tonnes-Priddy L, Hoffmann J, Csepregi A, Röcken C, Schulz HU, Malfertheiner P, Lofton-Day C. Genome scanning analysis identifies ALX4 gene methylation as a potential marker for colorectal and other gastrointestinal adenocarcinomas. Gastroenterology. 2006 Nov;131(5):1418-30
132. Ebert MPA, Niemeyer D, Deininger SO, Wex T, Knippig C, Hoffmann J, Sauer J, Albrecht W, Malfertheiner P, Röcken C. Identification of increased fibrinopeptide A serum protein levels in gastric cancer sera by magnet bead assisted MALDI-TOF mass spectrometry. J Protome Res. 2006;5(9):2152-2158
131. Carl-McGrath, Lendeckel U, Ebert M, Röcken C. Ectopeptidases in tumour biology: a review. Histol Histopathol. 2006;21(12):1339-53
130. Ebert MPA, Yu J, Röcken C. Proteomics in gastroinestinal cancers. Ann Oncol. 2006; Suppl. 10:x253-x258
129. Schulz S, Röcken C, Schulz S. Immunohistochemical detection of bombesin receptor subtypes GRP-R and BRS-3 in human tumors using novel anti-peptide antibodies. Virchows Arch. 2006; 449:421-427
128. Schulz S, Röcken C, Ebert MP, Schulz S. Immunocytochemical identification of low-affinity NTS2 neurotensin receptors in parietal cells of human gastric mucosa. J Endocrinol. 2006 Oct;191(1):121-8
127. Schulz S, Röcken C, Schulz S. Immunocytochemical localization of plasma membrane GHRH receptors in human tumors. Frequent expression in breast, ovarian and prostate carcinoma. Eur J Cancer. 2006;42(14):2390-6
126. Röcken C, Ernst J, Hund E, Michels H, Perz J, Saeger W, Sezer O, Spuler S, Willig F, Schmidt HHJ. Interdisziplinäre Leitlinien zur Diagnostik und Therapie der extrazerebralen Amyloidosen. Dtsch Med Wochenschr. 2006;131 Suppl 2:S45-66
125. Röcken C. Extrazerebrale Amyloidose – erste umfassende Leitlinie. Dtsch Med Wochenschr. 2006;131 Suppl 2:S44
124. Treiber G, Wex T, Röcken C, Fostitsch P, Malfertheiner P. Impact of biomarkers on disease survival and progression in patients treated with octreotide for advanced hepatocellular carcinoma. J Cancer Res Clin Oncol. 2006;132(11):699-708
123. Ebert MP, Röcken C. Molecular screening of gastric cancer by proteome analysis. Eur J Gastroenterol Hepatol. 2006;18:847-53
122. Daigeler A, Kuci H, Altmann S, Schneider W, Röcken C Extramedullary multiple myeloma associated with amyloidomas of the lower limb. Plast Reconstr Surg. 2006;117:2530-2
121. Kebbel A, Röcken C. Immunohistochemical classification of amyloid revisited. Am J Surg Pathol. 2006;30:673-83.
120. Preller V, Gerber A, Togni M, Wrenger S, Schraven B, Röcken C, Marguet D, Ansorge S, Brocke S, Reinhold D. CD26/DP IV in T cell activation and autoimmunity. Adv Exp Med Biol. 2006;575:187-93.
119. Schulz S, Stumm R, Röcken C, Mawrin C, Schulz S. Immunolocalization of full-length NK1 tachykinin receptor in human tumors. J Histochem Cytochem. 2006; 54(9):1015-20
118. Csepregi A, Röcken C, Treiber G, Malfertheiner P. Budesonide in autoimmune hepatitis.World J Gastroenterol. 2006; 12:1362-1366
117. Qiao L, Zhang H, Yu J, Francisco R, Dent P. Ebert MPA, Röcken C, Farrell G. Constitutive Activation of NF-kB in Human Hepatocellular Carcinoma: Evidence of a Cytoprotective Role. Human Gene Therapy. 2006; 17:280-290
115. Röcken C, Tautenhahn J, Bühling F, Sachwitz D, Vöckler S, Goette A, Bürger T. Prevalence and pathology of amyloid in atherosclerotic arteries. Arteriosclerol Thromb Vasc Biol. 2006; 26:676-7
114. Mönkemüller K, Weigt J, Treiber G, Kolfenbach S, Kahl S, Röcken C, Ebert M, Fry LC Malfertheiner P. Diagnostic and therapeutic impact of double-balloon enteroscopy. Endoscopy. 2006; 38:67-72
113. Ebert MPA, Korc M, Malfertheiner P, Röcken C. Advances, challenges and limitations in serum-proteome based cancer-diagnosis. J Proteome Res. 2006 Jan;5(1):19-25
112. Yu J, Qiao L, Zimmermann L, Francisco R, Ebert MPA, Röcken C, Lin W, Teoh N, Malfertheiner P, Farrell GC. Troglitazone inhibits tumor growth in hepatocellular carcinoma in vitro and in vivo. Hepatology. 2006;43:134-43
111. Röcken C, Becker K, Fändrich M, Schroeckh V, Stix B, Rath T, Kähne T, Dierkes J, Roessner A, Albert FW. ALys amyloidosis caused by compound heterozygosity in exon 2 (Thr70Asn) and exon 4 (Trp112Arg) of the lysozyme gene. Hum Mutation. 2006 Jan;27(1):119-20
110. Chen J, Röcken C, Nitsche B, Hosius C, Gschaidmeier H, Kahl S, Malfertheiner P, Ebert MPA. The tyrosine kinase inhibitor imatinib fails to inhibit pancreatic cancer progression. Cancer Lett. 2006 Feb 28; 233(2):328-37
2005
109. Ebert MPA, Lendeckel U, Dierkes J, Folwaczny C, Roessner A, Stolte M, Malfertheiner P, Röcken C. The angiotensin I-converting enzyme gene insertion/deletion polymorphism is linked to early gastric cancer. Cancer Epidemiol Biomarkers Prev. 2005;14:2987-9
108. Röcken C, Wilhelm S. Influence of tissue fixation on the extraction and identification of amyloid proteins. J Lab Clin Med. 2005; 146:244-250
107. Gregorini G, Izzi C, Obici L, Tardanico R, Röcken C, Viola BF, Capistrano M, Donadei S, Biasi L, Scalvini T, Merlini G, Scolari F. Renal Apolipoprotein A-I Amyloidosis: A Rare Cause of Hereditary Tubulo-Interstitial Nephritis. J Am Soc Nephrol. 2005; 16:3680-6
106. Ebert MPA, Mooney S, Tonnes-Priddy L, Lograsso J, Chen J, Röcken C, Schulz HU, Malfertheiner P, Lofton-Day C. Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancer. Neoplasia. 2005;7:771-778
105. Foitschik T, Saeger W, Riebe M, Röcken C. Advanced glycation end products in intervertebral discs and hip joint capsules: Correlation to senile amyloid? Amyloid. 2005; 12:167-73
104. Röcken C, Licht J, Roessner A, Carl-McGrath S. Canalicular immunostaining of aminopeptidase N (CD13) as a diagnostic marker for hepatocellular carcinomas. J Clin Pathol. 2005; 58:1069-1075
103. Schulz S, Röcken C, Mawrin C, Schulz SImmunocytochemical localization of CCK1 Cholecystokinin Receptors in Normal and Neoplastic Human Tissues. J Clin Endocrinol Metab. 2005; 90: 6149-55
102. Ochel HJ, Gademann G, Röcken C, Wördehoff H. Effects of Imatinib Mesylate on Adenoid Cystic Carcinomas. Anticancer Research. 2005; 25:3659-3664
101. Ebert MPA, Schäfer C, Chen J, Hoffmann J, Gu P, Kubisch C, Carl-McGrath S, Treiber G, Malfertheiner P, Röcken C. Protective Role of Heat Shock Protein 27 in Gastric Mucosal Injury. J Pathol. 2005; 207:177-184
100. Krüger S, Kalinski T, Hundertmark T, Wolf H, Wex T, Peitz U, Nägler D, Malfertheiner P, Naumann M, Röcken C, Roessner A. Up-regulation of cathepsin X in H. pylori-gastritis and gastric cancer. J Pathol. 2005; 207:32-42
99. Eder F, Schulz HU, Röcken C, H Lippert. A case of solid-pseudopapillary tumor of the pancreatic tail. World J Gastroenterol. 2005; 11:4117-4119
98. Csepregi A, Treiber G, Röcken C, Malfertheiner P. Twinrix induced severe jaundice as the first clinical manifestation of autoimmune hepatitis. World J Gastroenterol. 2005; 11: 4114-4116
97. Linke RP, Joswig R, Murphy CL, Wang S, Zhou H, Gross U, Röcken C, Westermark P, Weiss DT, Solomon A. Senile seminal vesicle amyloid is derived from semenogelin I. J Lab Clin Med. 2005; 145: 187-193
96. Chen J, Röcken C, Hoffmann J, Krüger S, Lendeckel U, Rocco A, Pastorekova S, Malfertheiner P, Ebert MPA. Expression of carbonic anhydrase IX (CA9) at the invasion front of gastric cancer. Gut. 2005; 54:920-927
95. Röcken C, Menard R, Bühling F, Vöckler S, Raynes J, Stix B, Krüger S, Roessner A, Kähne T. Proteolysis of serum amyloid A and AA amyloid proteins by cysteine proteases: cathepsin B generates AA amyloid proteins and cathepsin L might prevent their formation. Ann Rheum Dis. 2005; 64: 808-815
94. Gellermann GP, Appel TR, Tannert A, Radestock A, Hortschanski P, Schroeckh V, Leisner C, Lütkepohl T, Sthrasburg S, Röcken C, Pras M, Linke RP, Diekmann S, Fändrich M . Raft lipids as novel and common components of human, extracellular amyloid fibrils. Proc. Natl. Acad. Sci. U.S.A. 2005;102: 6297-302
93. Bühling F, Wille A, Röcken C, Wiesner O, Welte T, Pap T. Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis. Respiratory Res. 2005;6:37
92. Ebert MPA, Lamer S, Meuer J, Malfertheiner P, Buschmann T, Röcken C, Seibert V Identification of the thrombin light chain A as the single best mass for differentiation of gastric cancer patients from individuals with dyspepsia by proteome analysis. J Proteome Res. 2005; 4: 586-590
91. Röcken C, Lendeckel U, Dierkes J, Westphal J, Carl-McGrath S, Peters B, Krüger S, Malfertheiner P, Roessner A, Ebert MPA. The number of lymph node metastases in gastric cancer correlates with the angiotensin I-converting enzyme gene insertion/deletion polymorphism. Clin Cancer Res. 2005; 11: 2526-2530
90. Stix B, Leber M, Bingemer P, Gross C, Rüschoff J, Fändrich M, Schoderet D, Vorwerk C, Zacharias M, Roessner A, Röcken C. Hereditary lattice corneal dystrophy is associated with corneal amyloid deposits enclosing C-terminal fragments of kerato-epithelin. Invest Ophthalmol Vis Sci. 2005; 46:1133-1139
89. Ebert M, Krüger S, Fogeron ML, Lamer S, Chen J, Pross M, Schulz HU, Lage H, Heim S, Roessner A, Malfertheiner P, Röcken C. Overexpression of Cathepsin B in gastric cancer identified by proteome analysis. Proteomics. 2005; 5:1693-704
88. Lendeckel U, Müller C, Röcken C, Laube B, Täger M, Huth C, Klein HU, Goette A. Expression of opioid receptor subtypes and their ligands in fibrillating human atria. PACE Suppl. 2005; 28: S275-S279
87. Evert M, Wardelmann E, Nestler G, Schulz HU, Roessner A, Röcken C. Abdominopelvic perivascular epithelioid cell sarcoma (malignant PEComa) with expression of c-kit (CD117). Histopathology. 2005; 46:108-117
86. Carl-McGrath S, Lendeckel U, Ebert M, Roessner A, Röcken C. The disintegrin-metalloproteinases ADAM-9, ADAM-12, and ADAM-15 are upregulated in gastric cancer. Int J Oncol. 2005; 26(1):17-24
85. Lendeckel U, Kohl J, Arndt M, Carl-McGrath S, Donat H, Röcken C. Increased expression of ADAM family members in human breast cancer and . breast cancer cell lines. J Cancer Res Clin Oncol. 2005; 131:41-48
84. Koester MO, Pross M, Dormann A, Röcken C, Lippert H, Huchzermeyer H. Multiple Rundherde der Leber bei einer 33-jährigen Patientin - Falldarstellung einer ungewöhnlichen Differentialdiagnose. Internist. 2005;46(1):69-74
83. Chen J, Röcken C, Lofton-Day C, Schulz HU, Müller O, Kahmann S, Malfertheiner P, Ebert MPA. Molecular analysis of APC promoter methylation and protein expression in colorectal cancer metastasis. Carcinogenesis. 2005; 26:37-43
2004
82. Chen J, Röcken C, Malfertheiner P, Ebert MPA. Recent advances in molecular diagnosis and therapy of gastric cancer. Dig Dis. 2004; 22: 380-385
80. Ebert MPA, Meuer J, Wiemer J, Schulz HU, Reymond M, Traugott U, Malfertheiner P, Röcken C. Identification of gastric cancer patients by serum protein profiling. J Proteome Res. 2004; 3: 1261-1266
79. Schulz S, Röcken C, Mawrin C, Weise W, Höllt V, Schulz S. Immunocytochemical ientification of VPAC1, VPAC2 and PAC1 receptors in normal and neoplastic human tissues using subtype-specific antibodies. Clin Cancer Res. 2004; 10: 8235-8242
78. Chen J, Röcken C, Klein-Hitpass, Malfertheiner P, Ebert MPA. Microarray analysis of gene expression in metastatic cancer cells exposed to the methylation inhibitor 5-aza-2′-deoxycytidine. Clin Exp Metastasis. 2004; 21: 389-397
77. Chen J, Kähne T, Röcken C, Götze T, Yu J, Sung JJY, Chen M, Hu P, Malfertheiner P,. Ebert MPA. Proteome analysis of gastric cancer metastasis by two-dimensional gel electrophoresis and matrix assisted laser desorption/ionization-mass spectrometry for identification of metastasis-related proteins. J Proteome Res. 2004; 3:1009-1016
76. Carl-McGrath S, Lendeckel U, Ebert M, Wolter AB, Roessner A, Röcken C. The ectopeptidases CD10, CD13, CD26, and CD143 are upregulated in gastric cancer. Int J Oncol. 2004; 25: 1223-1232
75. Bühling F, Röcken C, Brasch F, Hartig R, Yasuda Y, Saftig P, Brömme D, Welte T. Pivotal role of cathepsin K in the prevention of lung fibrosis. Am J Pathol. 2004; 164: 2203-2216
74. Waldburg N, Kähne T, Reisenauer A, Röcken C, Welte T, Bühling F. Clinical proteomics in lung disease. Path Res Pract. 2004; 200: 69-82
73. Bohne S, Sletten K, Menard R, Bühling F, Vöckler S, Wrenger E, Roessner A, Röcken C. Cleavage of AL amyloid proteins by Cathepsin B, K and L. J Pathol. 2004; 203:528-537
72. Röcken C, Carl-McGrath S, Gräntzdörffer I, Mantke R, Roessner A, Lendeckel U. Ectopeptidases are differentially expressed in hepatocellular carcinomas. Int J Oncol. 2004; 24:487-495
71. Gräntzdörffer I, Lendeckel U, Carl-McGrath S, Roessner A, Röcken C. Angiotensin I-converting enzyme (CD 143) is down-regulated in focal nodular hyperplasia of the liver. Am J Surg Pathol. 2004: 28: 84-88
70. Evert M, Roessner A, Röcken C. Synchronous granulomatous cholecystitis and fibroelastosis of the gallbladder. Virchows Archiv. 2004; 445(6): 655-658
69. Mahlfeld K, Graßhoff H, Jentsch-Ullrich K, Röcken C, Franke J. Sonographischer Nachweis einer Osteolyse bei solitärem Plasmozytom des Sternums. Zentralbl Chir. 2004; 129(1):63-66
68. Götte A, Röcken C . Atrial amyloidosis and atrial fibrillation: A gender-dependent "arrhythmogenic substrate"? Eur Heart J. 2004; 25:1185-1186
67. Röcken C, Ebert MPA, Roessner A. Proteomics in Pathology Research and Practice. Path Res Pract. 2004; 200(2): 69-82
66. Röcken C. Proteomics in Pathology Research and Practice. Path Res Pract. 2004; 200(2): 67-67
64. Götte A, Jentsch-Ullrich K, Lendeckel U, Röcken C, Agbaria M, Mohren M, Auricchio A, Mohren M, Franke A, Klein HU. Effect of atrial fibrillation on hematopoietic progenitor cells. A novel pathophysiologic role of the atrial natriuretic peptide? Circulation. 2003; 108:2446-2449
63. Vogt S, Schneider-Stock R, Klauck S, Roessner A, Röcken C. Detection of hepatitis C virus RNA in formalin-fixed, paraffin embedded thin needle liver biopsies specimens. Am J Clin Pathol. 2003; 120(4):536-543
62. Juhasz M, Ebert MPA, Schulz HU, Röcken C, Molnar B, Tulassay Z, Malfertheiner P. Dual role of serum soluble E-cadherin as an indicator of metastatic development in gastric cancer. Scand J Gastroenterol. 2003; 38:850-855
61. Ebert MPA, Ju Y, Hoffmann J, Rocco A, Röcken C, Kahmann S, Müller O, Korc M, Sung JJ, Malfertheiner P. Loss of b-catenin expression in metastatic gastric cancer. J Clin Oncol. 2003; 21(9):1708-1714
60. Röcken C, Kientsch-Engel R, Mansfeld S, Stix B, Schwan M, Stubenrauch K, Weigle B, Bühling F, Schwan M, Saeger W. Advanced glycation end products in AA amyloidosis. Am J Pathol. 2003; 162:1213-1220
59. Petz D, Klauck S, Röhl FW, Malfertheiner P, Roessner A, Röcken C. Feasibility of histological grading and staging of chronic viral hepatitis using specimens obtained by thin needle biopsy. Virchows Archiv. 2003; 442:238-244
58. Mawrin C, Brunn A, Röcken C, Schröder JM. Peripheral neuropathy in systemic lupus erythematosus: pathomorphological features and distrubtuion pattern of matrix metalloproteinases. Acta Neuropathologica. 2003; 105:365-372
57. Kellner U, Jacobsen A, Kellner A, Mantke R, Roessner A, Röcken C. Comparative genomic hybridization: Synchronous occurrence of focal nodular hyperplasia and hepatocellular carcinoma in the same liver is not based on common chromosomal aberrations. Am J Clin Pathol. 2003; 119:265-271
56. Chen J, Chen M, Röcken C, Götze T, Malfertheiner P, Ebert MPA. Molecular therapy of gastric cancer. Cancer Therapy 2003; 12(1): 321-331
55. Fels L, Buschmann T, Meuer J, Raymond MA, Lamer S, Röcken C, Ebert M. Proteome analysis for the identification of tumor-associated biomarkers in gastrointestinal cancer. Dig Dis. 2003; 21:292-298
54. Röcken C, Sletten K. Amyloid in surgical pathology. Virchows Archiv. 2003; 443:3-16
53. Götte A, Röcken C, Nepple K, Lendeckel U. Proteases and Arrhythmias.. In: Lendeckel U, Hooper NM (Hrsg.) Proteases in biology and disease. Proteases in tissue remodeling of lung and heart. Kluwer-Academic/Plenum Publishers, New York, 2003; S. 191-218
52. Peitz U, Röcken C. Lebererkrankungen bei Alpha-1 Antitrypsinmagel. In: Alpha-1 Antitrypsinmangel. Referenz für Klinik und Praxis. In: Köhlein T, Welte T (Hrsg.) UNI-MED, Bremen, 2003; S. 40-45
2002 - 1992
51. Röcken C, Peters B, Juenemann G, Saeger W, Klein HU, Huth C, Roessner A, Goette A. Atrial amyloidosis: An arrhythmogenic substrate for persistent atrial fibrillation. Circulation. 2002; 106:2091-2097
50. Bühling F, Waldburg N, Krüger S, Röcken C, Wiesner O, Weber E, Welte T. Expression of cathepsins B, H, K, L, and S during human fetal lung development. Dev. Dyn. 2002; 225:14-21
49. Mantke R, Röcken C, Schubert D, Pross M, Sokolowski A, Halangk W, Lippert H, Schulz HU. Enzymatic and histological alterations in the isolated perfused rat pancreas under conditions of oxidative stress. Langenbecks Arch Surg. 2002; 387:170-176
48. Götte A, Arndt M, Röcken C, Staack T, Bechtloff R, Reinhold D, Huth C, Ansorge S, Klein HU, Lendeckel U. Calpains and cytokines in fibrillating human atria. Am J Physiol. 2002; 283:H264-H272
47. Röcken C, Kronsbein H, Sletten K, Roessner A, Bässler R. Amyloidosis of the breast. Virchows Archiv. 2002; 440:527-535
46. Götte A, Juenemann G, Klein HU, Peters B, Roessner A, Huth C, Röcken C. Determinants and consequences of atrial fibrosis in patients undergoing open heart surgery. Cardiovascular Res. 2002; 54:390-396
45. Arndt M, Lendeckel U, Röcken C, Nepple K, Wolke C, Spiess A, Huth C, Ansorge S, Klein HU, Goette A. Altered expression of ADAMs (a disintegrin and metalloproteinase) in fibrillating human atria. Circulation. 2002; 105:720-725
44. Wieker K, Röcken C, Koenigsmann M, Roessner A, Franke A. MALT-lymphoma and pulmonary amyloidosis. A case report. Amyloid. 2002; 9:190-193
43. Knippig C, Röcken C, Roessner A, Neumann W, Malfertheiner P. Schultermetastase als Erstmanifestation eines hepatozellulären Karzinoms (HCC). Med Klinik. 2002; 97:361-364
42. Wrenger E, Röcken C, Dietzmann J, Grote HJ, Roessner A, Neumann KH. Ambulatory treatment with intravenous norepinephrine in a patient with end stage renal failure and generalized AA amyloidosis. Amyloid. 2002; 9:47-51
41. Röcken C. Differentialdiagnose der Amyloidose. Verh Dtsch Ges Path. 2002; 86:107-115
40. Röcken C. 16th Amyloidforum organized by the German Society of Amyloid Diseases, April 2002 in Vienna, Austria. Amyloid. 2002; 9:207-211
39. Röcken C, Shakespeare A. Pathology, diagnosis, and pathogenesis of AA amyloidosis.. Virchows Archiv. 2002; 440:111-122
38. Röcken C, Meier H, Klauck S, Wolff S, Malfertheiner P, Roessner A. Large needle biopsy versus thin needle biopsy in diagnostic pathology of liver diseases. Liver. 2001; 21:391-397
37. Schubert D, Mantke R, Pross M, Röcken C, Sokolowski A, Halangk W, Lippert H, Schulz HU. Enzymatische und histologische Veränderungen am isoliert perfundierten Pankreas der Ratte im Taurocholat- und Cerulein-Modell der akuten Pankreatitis. Zentralbl Chir. 2001; 126:934-938
36. Borscheri N, Roessner A, Röcken C. Canalicular immunostaining of neprilysin (CD10) as a diagnostic marker of hepatocellular carcinomas. Am J Surg Pathol. 2001; 25:1297-1303
35. Bühling F, Reisenauer A, Gerber A, Krüger S, Weber E, Brömme D, Roessner A, Ansorge S, Welte T, Röcken C. Cathepsin K - a marker of macrophage differentiation? J Pathol. 2001; 195:375-382
34. Stix B, Kähne T, Sletten K, Raynes J, Roessner A, Röcken C. Proteolysis of AA amyloid fibril proteins by matrix metalloproteinases-1, -2, and –3. Am J Pathol. 2001; 159:561-570
33. Mantke R, Ridwelski K, Röcken C, Pross M, Schulz HU, Lippert H. Das hepatobiliäre Zystadenom. Chirurg. 2001; 72:277-280
32. Röcken C, Stix B, Brömme D, Ansorge S, Roessner A, Bühling F. A putative role for cathepsin K in degradation of AA and AL amyloidosis. Am J Pathol. 2001; 158:1029-1038
31. Röcken C, Carl-McGrath S. Pathology and pathogenesis of hepatocellular carcinoma.. Dig Dis. 2001; 19:269-278
30. Müller D, Roessner A, Röcken C. Distribution pattern of matrix metalloproteinases (MMP-1, -2, -3, and -9), tissue inhibitors of matrix metalloproteinases (TIMP-1 and -2), and a2-macroglobulin in cases of generalized AA and AL amyloidosis. Virchows Arch. 2000; 437:521-527
29. Steusloff K, Röcken C, Saeger W. Basement membrane proteins and apolipoprotein E in growth hormone secreting adenomas and their correlation to amyloid: an immunoelectron microscopic study. Endocr Pathology. 2000; 11:49-56
28. Götte A, Arndt M, Röcken C, Staack T, Geller JC, Huth C, Ansorge S, Klein HU, Lendeckel U. Regulation of angiotensin II receptor subtypes during atrial fibrillation. Circulation 2000; 101:2678-269
27. Götte A, Staack T, Röcken C, Arndt M, Geller JC, Huth C, Ansorge S, Klein HU, Lendeckel U . Increased expression of extracellular-signal regulated kinases and angiotensin-converting enzyme in human atria during atrial fibrillation. J Am Coll Cardiol 2000; 35:1669-1677
26. Röcken C, Hegenbarth V, Schmitz M, Stix B, Schade G, Mohnert A, Roessner A. Plasmacytoma of the tonsil with secondary AL amyloidosis and osseous metaplasia. Virchows Archiv. 2000; 436(4):336-344
25. Pap G, Eberhardt R, Röcken C, Nebelung W, Neumann HW, Roessner A. Expression of stromelysin and urokinase type plasminogen activator protein in resection specimens and biopsies at different stages o osteoarthritis of the knee. Path Res Pract. 2000; 196:219-226
24. Bässler R, Würstlein R, Röcken C, Christ F. Tumorförmige bilaterale Amyloidose der Mamma assoziiert mit einem invasiven lobulären Karzinom und Sjögren-Syndrom. Kasuistik und Literaturübersicht. Geburtshilfe und Frauenheilkunde. 2000; 60:645-650
23. Röcken C, Pross M, Brucks U, Ridwelski C, Roessner A. Cholangiocarcinoma occurring in a liver with multiple bile duct hamartomas (von Meyenburg complexes). Arch Pathol Lab Med. 2000; 124:1704-1706
22. Röcken C, Wieker K, Grote HJ, Müller G, Franke A, Roessner A. Rosai-Dorfman disease and generalized AA amyloidosis. A case report. Hum Pathol. 2000; 31(5):621-624
21. Röcken C, Roessner A. An evaluation of antigen retrieval procedures for immunoelectron microscopical classification of amyloid deposits.. J Histochem Cytochem. 1999; 47:1385-94
20. Röcken C, Schneider-Stock R, Buhtz P, Manger T, Roessner A. Hepatic angiomyolipoma in a 26-year-old Caucasian woman with a history of tibial osteosarcoma. Path Res Pract. 1999; 195:765-772
19. Röcken C, Radun D, Glasbrenner B, Malfertheiner P, Roessner A. Generalized AA-amyloidosis in a 58-year-old Caucasian woman with an 18-month history of gastrointestinal tuberculosis. Virchows Archiv. 1999; 434:95-100
18. Mohr A, Miehlke S, Klauck S, Röcken C, Malfertheiner P. Hepatomegaly and cholestasis as primary clinical manifestation of an AL-kappa amyloidosis. Eur J Gastroenterol Hepatol. 1999; 11:921-925
17. Glasbrenner B, Güthner C, Röcken C, Mattfeld T, Hetzel W, Adler G. 56jähriger Patient mit segmental florider Colitis und Colonamyloidose. Internist. 1999; 40:668-672
16. Steusloff K, Röcken C, Saeger W. Basement membrane proteins, apolipoprotein E and glycosaminoglycans in pituitary adenomas and their correlation to amyloid. Virchows Archiv. 1998; 433:29-34.
15. Röcken C, Kisilevsky R. Comparison of the binding and endocytosis of high-density lipoprotein from healthy (HDL) and inflamed (HDLSAA) donors by murine macrophages of four different mouse strains. Virchows Archiv. 1998; 432:547-555
14. Saeger W, Röcken C. Amyloid: Mikroskopischer Nachweis, Klassifikation und klinischer Bezug. Pathologe. 1998; 19:345-354
13. Röcken C, Kisilevsky R. Binding and endocytosis of murine high density lipoprotein from healthy (HDL) and inflamed donors (HDLSAA) by murine macrophages in vitro. A light- and electronmicroscopic investigation. Amyloid. 1997; 4:259-273
12. Röcken C, Paris D, Steusloff K, Saeger W. Investigation of the presence of apolipoprotein E, glycosaminoglycans, basement membrane proteins, and protease inhibitors in senile interstitial amyloid of the pituitary. Endocr Pathol. 1997; 8:205-214
11. Röcken C, Schwotzer E, Linke RP, Saeger W. The classification of amyloid deposits in clinicopathological practice. Histopathology. 1996; 29:325-335
10. Röcken C, Eick B, Saeger W. Senile amyloidoses of the pituitary and adrenal glands. Morphological and statistical investigations. Virchows Arch. 1996; 429:293-299
8. Röcken C, Linke RP, Saeger W. Corpora amylacea in the lung, prostate and uterus: A comparitive immunohistochemical study. Path Res Pract. 1996; 192:998-1006
7. Röcken C, Saeger W, Fleege JC, Linke RP. Interstitial amyloid deposits in the pituitary gland: Morphometry, immunohistology, and correlation to diseases. Arch Pathol Lab Med. 1995; 119:1055-1060
6. Röcken C, Uhlig H, Saeger W, Linke RP, Fehr S. Amyloid deposits in pituitaries and pituitary adenomas: Immunohistochemistry and in situ hybridization. Endocr Pathol. 1995; 6:135-143
5. Röcken C, Saeger W, Linke RP. Gastrointestinal amyloid deposits in old age. Report on 110 consecutive autopsical patients and 98 retrospective bioptic specimens. Path Res Pract. 1994; 190:641-649
4. Röcken C, Saeger W. Amyloid deposits of the pituitary in old age: Correlation with histopathological alterations. Endocr Pathol. 1994; 5:183-190
3. Saeger W, Röcken C, Linke RP. Amyloiddiagnostik in der klinischen Pathologie. HÄB. 1993; 1:9-14
2. Röcken C, Saeger W, Linke RP. Mehrere unterschiedliche Amyloidtypen bei einer 93-jährigen Patientin: Kasuistik eines Sektionsfalles.. Pathologe. 1993; 14:42-46
1. Röcken C, Linke RP, Saeger W. Immunohistology of islet amyloid polypeptide in diabetes mellitus: semiquantitative studies in a post-mortem series. Virchows Archiv [A]. 1992; 421:339-344
